Syndrome de lyse tumorale

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Révision datée du 18 juin 2020 à 09:39 par Julien (discussion | contributions) (Page créée avec « == Caractéristiques == hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia. These electrolyte abnormalities can lead to acute kidney injury, cardiac arrhythm... »)
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Caractéristiques

hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia. These electrolyte abnormalities can lead to acute kidney injury, cardiac arrhythmias, seizures, and death.

Traitement

Patients at intermediate risk for TLS can be managed with monitoring of laboratory values, hydration, and allopurinol, and those at high risk should receive intravenous hydration and rasburicase, a urate oxidase enzyme that metabolizes uric acid, before receiving chemotherapy.